Abstract: Family education guidance in schools is an effective way for school education and family education to realize common progress and co-education. Based on the theory of symbiosis in educational ecology, the practice of family education guidance in schools to promote family-school symbiosis and co-education is found to be faced with the practical dilemmas of insufficient linkage of symbiotic units, impeded evolution of symbiotic modes, and lack of support for symbiotic environments. In order to carry out family education guidance to promote family-school symbiosis, schools should strengthen the concept of family-school symbiosis, play the leading role of schools, and promote the linkage of symbiotic units; improve the guidance service system, smooth the interface of energy transfer, and promote the evolution of symbiotic patterns; and improve the construction of guidance systems, create a symbiotic culture between family and school, and form a positive symbiotic environment.